The company was founded in 2016 after winning the Scottish Higgs EDGE 2016 for its development of a Graphene layer manufacturing process. The transformational process is disruptive as it enables the use of Graphene in an unlimited number of applications. The company’s design for manufacture (DfM) process creates 3D graphene in seconds and therefore enables high volume manufacture.
To support the technical development team, we are looking for a hands-on scientist develop our novel graphene biosensor. You will join our multidisciplinary team and will develop assay reagents for multiple assays at our development facility.
Specific duties include:
- Preparation of antibody conjugates and antibody-coated graphene electrodes for assay development
- Development of new, and improvement of current, reagent preparation procedures and in-process testing
- Design, execution and analysis of appropriate experiments for assessing and improving assay reagent formulations
- Creating and maintaining quality records for reagent development progress and associated experiments
- Testing developed reagents against the required performance stability and cost requirements
- Writing and updating procedures
- Raising, investigating and closing non-conformances to agreed timelines
- Completing COSHH assessments when required
- Training new personnel on all appropriate procedures when required
- Technically reviewing change controls and peer reviewing laboratory notebooks
The successful candidate can demonstrate the following:
Education and Skills
- Relevant PhD in chemistry, biochemistry or relevant subject
- Significant relevant experience in a similar role within a GLP/GMP environment with experience in the Bio- immunoassay reagents and graphene chemistry
Essential Experience
- Experience and knowledge of different coupling chemistries, click chemistries and pi-pi interaction for functionalization of graphene electrodes with antibodies, enzymes, macromolecules, aptamers and supramolecules
- Experience and knowledge of different coupling chemistries for forming antibody-enzyme conjugates, and characterisation techniques used to assess performance of antibody conjugates
- Ability to run reference assays on clinical analysers
- Ability to write clear and concise protocols for complex reagent manufacturing procedures
- Detailed knowledge of diagnostic immunoassay technology
- Experience of working in a laboratory within GLP guidelines
- Data analysis skills
- High level of skills in problem solving and innovation
The following experience is highly beneficial but not essential
- Experience of developing particle-based, graphene based bio- immunoassays
- Working knowledge of electrochemical methods
- Experience and understanding of optimisation of the following: reagent stability, assay performance and batch to batch variability
- Experience and understanding of factors important in drying reagents for use in bio and immunoassays
- Knowledge and experience of working within a biohazard environment